Methamphetamine is an addictive stimulant drug that strongly activates certain systems in the brain. Methamphetamine is closely related chemically to amphetamine, but the central nervous system effects of methamphetamine are greater. Methamphetamine can be taken orally, injected, or inhale. Acute higher doses lead to enhanced stimulation of the central nervous system and induce euphoria, alertness, reduced appetite, and a sense of increased energy and power. Methamphetamine is excreted in the urine as amphetamine and oxidized and deaminated derivatives. However, 10 to 20 % of Methamphetamine is excreted unchanged. Thus, the presence of the parent compound in the urine indicates Methamphetamine use. These Identify Diagnostics drug tests yield a positive result when the concentration of Methamphetamine in urine exceeds 500 ng/mL. Also see our available cut-off level of 1,000 ng/ml.